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Timing of stress-hormone pulses controls weight gain

Timing of stress-hormone pulses controls weight gain

CSB faculty Dr. Mary Teruel (senior author), CSB graduate students Zahra Bahrami-Nejad and Michael Zhao (co-lead authors), CSB postdoc Dr. Stefan Tholen, CSB graduate student Mingyu Chung, and CSB alumni Dr. Devon Hunerdosse, Dr. Karen Tkach, and Sabine van Schie (co-authors) discovered that rising and falling levels of hormones known as glucocorticoids can affect weight gain.

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Amit Joshi, Nay L Shaw, Hannes Vogel, Anna D Cunningham, Mehrdad Shamloo, Daria Mochly-Rosen, and Carlos Gonzalez featured on the cover of EMBO Molecular Medicine

Amit Joshi, Nay L Shaw, Hannes Vogel, Anna D Cunningham, Mehrdad Shamloo, Daria Mochly-Rosen, and Carlos Gonzalez featured on the cover of EMBO Molecular Medicine

This image represents the open‐field test of an untreated mouse model of ALS that walks short distances and sticks to the edges of the open field, while the P110‐treated mouse model of ALS walks longer distances and enters the center of the field. The open field is here represented by the mitochondria, which is the main affected organelle in ALS that is corrected by P110 treatemnt. By Amit Joshi, Daria Mochly‐Rosen and colleagues: Inhibition of Drp1/Fis1 interaction slows progress of amyotrophic lateral sclerosis. Scientific image by Carlos Gonzales.

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