Publications

Stochastic Endogenous Replication Stress Causes ATR-Triggered Fluctuations in CDK2 Activity that Dynamically Adjust Global DNA Synthesis Rates.

Daigh LH, Liu C, Chung M, Cimprich KA, Meyer T. (2018) Cell Syst. 2018 Jun 4. pii: S2405-4712(18)30229-1. doi: 10.1016/j.cels.2018.05.011. [PubMed]

Invisible smoke: third-party endorsement and the resurrection of heat-not-burn tobacco products.

Elias J, Ling PM. (2018) Tob Control. 2018 Jun 6. pii:tobaccocontrol-2018-054433. doi: 10.1136/tobaccocontrol-2018-054433. [PubMed]

EMI1 switches from being a substrate to an inhibitor of APC/C(CDH1) to start the cell cycle.

Cappell SD, Mark KG, Garbett D, Pack LR, Rape M, Meyer T. (2018) Nature. 2018 Jun 6. doi: 10.1038/s41586-018-0199-7. [PubMed]

It’s not magic – Hsp90 and its effects on genetic and epigenetic variation.

Zabinsky RA, Mason GA, Queitsch C, Jarosz DF. (2018) Semin Cell Dev Biol. 2018 May 25. pii: S1084-9521(17)30367-1. doi: 10.1016/j.semcdb.2018.05.015. [PubMed]

Aldehyde dehydrogenase 3A1 activation prevents radiation-induced xerostomia by protecting salivary stem cells from toxic aldehydes.

Saiki JP, Cao H, Van Wassenhove LD, Viswanathan V, Bloomstein J, Nambiar DK, Mattingly AJ, Jiang D, Chen CH, Stevens MC, Simmons AL, Park HS, von Eyben R, Kool ET, Sirjani D, Knox SM, Le QT, Mochly-Rosen D. (2018) Proc Natl Acad Sci U S A. 2018 May 24. pii: 201802184. doi: 10.1073/pnas.1802184115. [PubMed]

Minimal Information About an Immuno-Peptidomics Experiment (MIAIPE).

Lill JR, van Veelen PA, Tenzer S, Admon A, Caron E, Elias J, Heck AJR, Marcilla M, Marino F, Müller M, Peters B, Purcell A, Sette A, Sturm T, Ternette N, Vizcaíno JA, Bassani-Sternberg M. (2018) Proteomics. 2018 May 23:e1800110. doi:10.1002/pmic.201800110. [PubMed]

Multiple Click-Selective tRNA Synthetases Expand Mammalian Cell-Specific Proteomics.

Yang AC, du Bois H, Olsson N, Gate D, Lehallier B, Berdnik D, Brewer KD, Bertozzi CR, Elias JE, Wyss-Coray T. (2018) J Am Chem Soc. 2018 May 18. doi:10.1021/jacs.8b03074. [PubMed]

Expression variation and covariation impair analog and enable binary signaling control.

Kovary KM, Taylor B, Zhao ML, Teruel MN. (2018) Mol Syst Biol. 2018 May 14;14(5):e7997. doi: 10.15252/msb.20177997. [PubMed]

Organizing biochemistry in space and time using prion-like self-assembly.

Jakobson CM, Jarosz DF. (2018) Curr Opin Syst Biol. 2018 Apr;8:16-24. doi: 10.1016/j.coisb.2017.11.012. Epub 2017 Dec 6. [PubMed]

Faulty replication can sting.

Crossley MP, Cimprich KA. (2018) Nature. 2018 May;557(7703):34-35. doi: 10.1038/d41586-018-02804-6. [PubMed]

MFN2 agonists reverse mitochondrial defects in preclinical models of Charcot-Marie-Tooth disease type 2A.

Rocha AG, Franco A, Krezel AM, Rumsey JM, Alberti JM, Knight WC, Biris N, Zacharioudakis E, Janetka JW, Baloh RH, Kitsis RN, Mochly-Rosen D, Townsend RR, Gavathiotis E, Dorn GW 2nd. (2018) Science. 2018 Apr 20;360(6386):336-341. doi: 10.1126/science.aao1785. [PubMed]

A Transcriptional Circuit Filters Oscillating Circadian Hormonal Inputs to Regulate Fat Cell Differentiation.

Bahrami-Nejad Z, Zhao ML, Tholen S, Hunerdosse D, Tkach KE, van Schie S, Chung M, Teruel MN. (2018) Cell Metab. 2018 Apr 3;27(4):854-868.e8. doi: 10.1016/j.cmet.2018.03.012. [PubMed]

Cardioprotection induced by a brief exposure to acetaldehyde:role of aldehyde dehydrogenase 2.

Ueta CB, Campos JC, Albuquerque RPE, Lima VM, Disatnik MH, Sanchez AB, Chen CH, Medeiros MHG, Yang W, Mochly-Rosen D, Ferreira JCB. (2018) Cardiovasc Res. 2018 Mar 20. doi: 10.1093/cvr/cvy070. [PubMed]

It pays to be in Phase

Itakura AK, Futia RA, Jarosz DF. (2018) Biochemistry. 2018 May 1;57(17):2520-2529. doi: 10.1021/acs.biochem.8b00205. Epub 2018 Mar 13. [PubMed]

CC-401 Promotes β-Cell Replication via Pleiotropic Consequences of DYRK1A/B Inhibition.

Abdolazimi Y, Lee S, Xu H, Allegretti P, Horton TM, Yeh B, Moeller HP, Nichols RJ, McCutcheon D, Shalizi A, Smith M, Armstrong NA, Annes JP. (2018) Endocrinology. 2018 Mar 5. doi: 10.1210/en.2018-00083. [PubMed]

T-cell immunopeptidomes reveal cell subtype surface markers derived from intracellular proteins.

Olsson N, Schultz LM, Zhang L, Khodadoust MS, Narayan R, Czerwinski DK, Levy R, Elias JE. (2018) Proteomics. 2018 Mar 1. doi: 10.1002/pmic.201700410. [PubMed]

Robustly Cycling Xenopus laevis Cell-Free Extracts in Teflon Chambers.

Chang JB, Ferrell JE Jr.. (2018) Cold Spring Harb Protoc. 2018 Feb 23. doi: 10.1101/pdb.prot097212. [PubMed]

A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.

Breslow DK, Hoogendoorn S, Kopp AR, Morgens DW, Vu BK, Kennedy MC, Han K, Li A, Hess GT, Bassik MC, Chen JK, Nachury MV. (2018) Nat Genet. 2018 Feb 19. doi: 10.1038/s41588-018-0054-7. [PubMed]

Genome-wide mapping of global-to-local genetic effects on human facial shape.

Claes P, Roosenboom J, White JD, Swigut T, Sero D, Li J, Lee MK, Zaidi A, Mattern BC, Liebowitz C, Pearson L, González T, Leslie EJ, Carlson JC, Orlova E, Suetens P, Vandermeulen D, Feingold E, Marazita ML, Shaffer JR, Wysocka J, Shriver MD, Weinberg SM. (2018) Nat Genet. 2018 Feb 19. doi: 10.1038/s41588-018-0057-4. [PubMed]

Monoamine oxidase-dependent endoplasmic reticulum-mitochondria dysfunction and mast cell degranulation lead to adverse cardiac remodeling in diabetes.

Deshwal S, Forkink M, Hu CH, Buonincontri G, Antonucci S, Di Sante M, Murphy MP, Paolocci N, Mochly-Rosen D, Krieg T, Di Lisa F, Kaludercic N. (2018) Cell Death Differ. 2018 Feb 19. doi: 10.1038/s41418-018-0071-1. [PubMed]

Transcriptome analysis and prognosis of ALDH isoforms in human cancer.

Chang PM, Chen CH, Yeh CC, Lu HJ, Liu TT, Chen MH, Liu CY, Wu ATH, Yang MH, Tai SK, Mochly-Rosen D, Huang CF. (2018) Sci Rep. 2018 Feb 9;8(1):2713. doi: 10.1038/s41598-018-21123-4. [PubMed]

Mapping Causal Variants with Single-Nucleotide Resolution Reveals Biochemical Drivers of Phenotypic Change.

She R, Jarosz DF. (2018) Cell. 2018 Jan 25;172(3):478-490.e15. doi: 10.1016/j.cell.2017.12.015. [PubMed]

Transcription-coupled changes in nuclear mobility of mammalian cis-regulatory elements.

Gu B, Swigut T, Spencley A, Bauer MR, Chung M, Meyer T, Wysocka J. (2018) Science. 2018 Jan 25. pii: eaao3136. doi: 10.1126/science.aao3136. [PubMed]

Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.

Calo E, Gu B, Bowen ME, Aryan F, Zalc A, Liang J, Flynn RA, Swigut T, Chang HY, Attardi LD, Wysocka J. (2018) Nature. 2018 Jan 24. doi: 10.1038/nature25449. [PubMed]

Inhibition of Drp1/Fis1 interaction slows progression of amyotrophic lateral sclerosis.

Joshi AU, Saw NL, Vogel H, Cunningham AD, Shamloo M, Mochly-Rosen D. (2018) EMBO Mol Med. 2018 Jan 15. pii: e8166. doi: 10.15252/emmm.201708166. [PubMed]