The Department of Chemical and Systems Biology explores the molecular mechanisms that underlie cellular function and contribute to human disease. Our laboratories emphasize interdisciplinary research that spans the biomedical sciences, including signal transduction, cell cycle regulation, chromatin remodeling, protein homeostasis, metabolism, and cell differentiation. By integrating genetic technologies, biochemical and chemical tools, quantitative measurements, and computational modeling, we strive to deconstruct these complex biological systems, predict emergent behaviors, and translate these discoveries into new medical therapies.
Read Carl Zimmer’s review on CSB professor Joanna Wysocka et al. Nature paper on the reactivation of our endogenous intrinsic retroviruses in the latest New York Times: Ancient Viruses, Once Foes, May Now Serve as Friends.