Stanford School of Medicine

Chemical & Systems Biology


Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.

Posted by CSB Department on July 1, 1998

Kontos CD, Stauffer TP, Yang WP, York JD, Huang L, Blanar MA, Meyer T, Peters KG. (1998) Mol. Cell. Biol. 18(7):4131-40 [PubMed]