Stanford School of Medicine

Chemical & Systems Biology


Ph.D. ProgramJoin the Chemical & Systems Biology Linkedin Group »

Qi Lab
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Using synthetic controllers of the genome (CRISPR interference or activation), we aim to understand how many genes coordinate quantitatively to affect cell fate decision.

Elias Lab
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Uncovering the mysteries of antibiotic associated diseases with mass spectrometry.

Ferrell Lab
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HeLa cells stained for cell cycle regulators.

Wysocka Lab
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Studies of cis-regulatory divergence reveal insights into human evolution and variation.

Jarosz Lab
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Understanding the impact of protein folding and misfolding in evolution, disease, and development.

Teruel Lab
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Systems biology of cell differentiation and cell signaling in the context of diabetes and cancer.

Wandless Lab
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New technologies for biological research with applications for mechanisms of protein quality control and immuno-oncology therapies.

Mochly-Rosen Lab
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Crystal structure of Alda-1, an isoform-selective chemical agonist of aldehyde dehydrogenase 2.

Chen Lab
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Live imaging of Hedgehog ligand-producing cells (green) and Gli-dependent transcription (red) during zebrafish development.

Meyer Lab
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MCF10A cells expressing the APC substrate Geminin-mCherry and Tubulin-YFP.

Cimprich Lab
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DNA fibers (blue) from cells sequentially labeled with halogenated nucleotides (red, green) to study replication fork progression and origin firing.

Advances In Basic Science And Molecular Medicine

The Department of Chemical and Systems Biology explores the frontiers of basic science and molecular medicine, particularly at the crossroads of cellular, chemical, and computational biology. We train Ph.D. students to apply genetic, chemical, cell biological, and quantitative methods to decipher the complex regulatory systems associated with normal physiology and disease states.

Specific research areas include cell signaling pathways, cell cycle control, epigenetics, cell fate specification, and genomic stability. The Chemical and Systems Biology Ph.D. program also emphasizes collaborative learning, and our research community includes scientists trained in molecular biology, cell biology, chemistry, physics, and engineering.

Our Ph.D. program consistently ranks among the top graduate training programs in the world. Most recently the National Research Council named us the top pharmacology-related training program in the United States, based on students’ GRE scores, faculty publications, median time to degree, program requirements, and training resources. The Chemical and Systems Biology graduate program was especially commended for the quality of its research activities.

Why Chemical And Systems Biology?

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How do cells achieve directed migration? Why doesn’t a skin cell become a neuron? How do drug-resistant cancers arise and how might they be prevented or overcome? Finding answers to these and other biomedical questions increasingly requires molecular, quantitative, and interdisciplinary approaches.

The Department of Chemical and Systems Biology is uniquely focused on understanding cell biology at the molecular and systems levels, and many of its faculty have expertise in biochemistry, chemistry, physics, and engineering. Developing novel technologies for basic research and translating discoveries into therapeutic strategies are also areas of special interest in the Chemical and Systems Biology community.

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Our goal is to train a new generation of scientists with the interdisciplinary skills and creative thinking required to tackle emerging challenges in biomedical research.  We invite all interested students to apply to the Chemical and Systems Biology Ph.D. program through the Stanford Biosciences online application form.  Applicants whose research interests match well with our scientific mission are encouraged to select Chemical and Systems Biology as their primary home program.